New medicine Cardione: to keep the heart and blood vessels healthy.

Do you think heart disease is a “privilege” for those over 50? This is not true. In the age of high speeds, colossal stress, malnutrition, chronic lack of sleep, bad habits, the heart began to wear out faster, and cardiovascular diseases, unfortunately, “rejuvenated”. Globally, the number of people over the age of 35 with cardiovascular disease is growing rapidly. The new drug Cardione is aimed at the treatment of cardiovascular insufficiency, atherosclerosis.

Benefits

• Improves the functioning of the heart muscle
• Reduces cholesterol levels
• Reduces the level of glucose in the blood
•  Clinically proven effective dose of taurine – 500 mg, which is optimal for treatment.
• Wide range of applications: cardiology, therapy, ophthalmology, endocrinology.
• Available without a prescription.
• Affordable price of a Russian manufacturer.
• Produced in accordance with the international GMP quality standard.

Nitrozamines – avoid using 

What many people don’t realize is that blood pressure pills contain trace amounts of nitrosamines, which, when taken in high amounts, increase the risk of diseases like cancer. It can also lead to severe liver damage.

In addition, all medicines contain many chemicals and preservatives that can seriously damage the body, especially organs such as the kidneys and liver. 

On the other hand, Cardione works and has no contraindications; everyone can use this medicine without worrying about future side effects.

Similarly, these natural blood pressure lowering pills work quickly, in less than 10 minutes after taking them, you will feel calm and your blood pressure will be restored. An important component of Cardione is taurine, a non-protein sulfur-containing β-amino acid (aminoethanesulfonic acid). Unlike other amino acids in the mammalian body, taurine is not metabolized or incorporated into cellular proteins, being the most abundant free amino acid in many tissues, including the brain, muscle tissue, and myocardium. In the myocardium, taurine is the main organic osmolyte1 and is found in a relatively high concentration – in humans, 25% of the pool of free amino acids (50% in other mammals). Although taurine can be synthesized endogenously from methionine and cysteine ​​in the presence of vitamin B6, compared to other mammals, humans have a low ability to synthesize it, and thus the main resource of taurine is food.

A wide spectrum of action of taurine is due to its metabolite nature and the regulatory effect of this compound on the functional state of the organs and systems of the body, as well as various types of metabolism in the body.

Taurine — influence on an organism 

Taurine is directly involved, first of all, in the metabolic processes of carbohydrate and protein metabolism, maintaining homeostasis of intracellular calcium and sodium concentrations, in the regulation of cell volume, stabilization of the cell membrane, neuromodulation, vasodilation, cardiac activity, learning and memory processes. Taurine has anti-atherogenic and hypotensive effects, and is involved in the development of the brain and retina. Taurine has been reported to protect visual function in diabetes and improve immune system function. In addition, it exhibits antitoxic and anti-inflammatory effects, inhibiting the proliferation of tumor cells. Taurine also protects various organs from damage, including psychological and oxidative stress, and has a cardioprotective effect during ischemia-reperfusion.

 The neuroprotective action Cardione is manifested in the improvement of cerebral circulation, cognitive functions, elimination of neurotic symptoms and somatovegetative disorders in patients with organic brain lesions. The role of taurine in the formation of bile acids and the absorption of fats is known. Cardione also has a hypoglycemic effect, and exhibits an inhibitory effect on the kallikrein-kinin system. Taurine reduces the manifestations of intoxication caused by the use of cardiac glycosides, potentiating their normalizing effect on the energy balance of the myocardium. 

Experimental studies of the drug Cardione

According to the preclinical study of the specific pharmacological activity of Cardione, a mild cardiotonic effect, high antianginal and coronary lytic activity of the drug were established. In experimental models, the drug improves blood circulation and the functional state of the ischemic focus, reduces lactate release by 2 times and normalizes the lactate/pyruvate ratio. The study drug increases the rate of coronary blood flow, myocardial oxygen supply and increases the oxygen content in the blood flowing from the coronary sinus, increasing the coronary reserve. At the same time, a summation effect is observed in terms of hemodynamic, coronary lytic, and cardioprotective activity, and a potentiation effect is observed in functional myocardial stability during exercise tests. 

It is convincing that under experimental conditions on animals, the studied drug causes hypodynamic shifts in systemic hemodynamic parameters and exhibits a positive inotropic effect in the acute period of myocardial infarction. In the experiment, Cardione exhibits a protective effect on the model of pituitrin-isadrin cardiomyopathy, preventing the death of animals and changes in myocardial contractility. Against the background of the aortic coarctation model in the compensation stage, Cardione prevents the development of tachycardia, increasing the rate of contractility.

Cardione will save you from heart ailments!